CVE-2026-100845

HIGH CVSS 4.0: 8.5 EPSS 0.14%
Updated Sep 30, 2026
Project-Monai
Parameter Value
CVSS 8.5 (HIGH)
Affected Versions before 1.6.0
Fixed In 1.6.0
Type CWE-502 (Deserialization of Untrusted Data)
Vendor Project-Monai
Public PoC No

MONAI before 1.6.0 contains an unsafe deserialization vulnerability in the NumpyReader class that unconditionally uses numpy.load with allow_pickle=True when loading .npy and .npz files. Attackers can craft malicious .npy files with pickle payloads that execute arbitrary code when loaded through MONAI's standard data pipeline.

Attack Parameters

Attack Vector
Local
Requires local access
Attack Complexity
Low
Easy to exploit
Attack Requirements
None
No additional conditions
Privileges Required
None
No privileges needed
User Interaction
Passive
Minimal interaction

Impact Assessment

Confidentiality
High
Complete data leak
Integrity
High
Complete data modification
Availability
High
Complete denial of service

CVSS Vector v4.0

Vulnerable Products 1

Configuration From (including) Up to (excluding)
Project-Monai Monai
cpe:2.3:a:project-monai:monai:*:*:*:*:*:*:*:*
— 1.6.0