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CVE-2026-31962

HIGH CVSS 4.0: 8.8 EPSS 0.06%
Updated Mar 19, 2026
Htslib
Parameter Value
CVSS 8.8 (HIGH)
Affected Versions 1.22 — 1.22.2
Fixed In 1.21.1
Type CWE-122 (Heap-based Buffer Overflow), CWE-125 (Out-of-bounds Read), CWE-129 (Improper Validation of Array Index), CWE-787 (Out-of-bounds Write)
Vendor Htslib
Public PoC No

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. While most alignment records store DNA sequence and quality values, the format also allows them to omit this data in certain cases to save space. Due to some quirks of the CRAM format, it is necessary to handle these records carefully as they will actually store data that needs to be consumed and then discarded.

Unfortunately the `cram_decode_seq()` did not handle this correctly in some cases. Where this happened it could result in reading a single byte from beyond the end of a heap allocation, followed by writing a single attacker-controlled byte to the same location. Exploiting this bug causes a heap buffer overflow.

If a user opens a file crafted to exploit this issue, it could lead to the program crashing, or overwriting of data and heap structures in ways not expected by the program. It may be possible to use this to obtain arbitrary code execution. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue.

There is no workaround for this issue.

Attack Parameters

Attack Vector
Network
Can be exploited remotely
Attack Complexity
Low
Easy to exploit
Attack Requirements
None
No additional conditions
Privileges Required
None
No privileges needed
User Interaction
None
No user interaction needed

Impact Assessment

Confidentiality
Low
Partial data leak
Integrity
High
Complete data modification
Availability
Low
Partial disruption

CVSS Vector v4.0

Vulnerable Products 3

Configuration From (including) Up to (excluding)
Htslib Htslib
cpe:2.3:a:htslib:htslib:*:*:*:*:*:*:*:*
1.21.1
Htslib Htslib
cpe:2.3:a:htslib:htslib:*:*:*:*:*:*:*:*
1.22 1.22.2
Htslib Htslib
cpe:2.3:a:htslib:htslib:1.23:*:*:*:*:*:*:*