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CVE-2026-31965

MEDIUM CVSS 4.0: 6.9 EPSS 0.02%
Updated Mar 19, 2026
Samtools
Parameter Value
CVSS 6.9 (MEDIUM)
Affected Versions 1.22 — 1.22.2
Fixed In 1.21.1
Type CWE-129 (Improper Validation of Array Index), CWE-125 (Out-of-bounds Read)
Vendor Samtools
Public PoC No

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. In the `cram_decode_slice()` function called while reading CRAM records, validation of the reference id field occurred too late, allowing two out of bounds reads to occur before the invalid data was detected. The bug does allow two values to be leaked to the caller, however as the function reports an error it may be difficult to exploit them.

It is also possible that the program will crash due to trying to access invalid memory. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

Attack Parameters

Attack Vector
Network
Can be exploited remotely
Attack Complexity
Low
Easy to exploit
Attack Requirements
None
No additional conditions
Privileges Required
None
No privileges needed
User Interaction
None
No user interaction needed

Impact Assessment

Confidentiality
Low
Partial data leak
Integrity
None
No data modification
Availability
Low
Partial disruption

CVSS Vector v4.0

Vulnerable Products 3

Configuration From (including) Up to (excluding)
Htslib Htslib
cpe:2.3:a:htslib:htslib:*:*:*:*:*:*:*:*
1.21.1
Htslib Htslib
cpe:2.3:a:htslib:htslib:*:*:*:*:*:*:*:*
1.22 1.22.2
Htslib Htslib
cpe:2.3:a:htslib:htslib:1.23:*:*:*:*:*:*:*