CVE-2026-54604

MEDIUM CVSS 4.0: 5.3 EPSS 0.30%
Updated Sep 23, 2026
Openslide
Parameter Value
CVSS 5.3 (MEDIUM)
Type CWE-758, CWE-908 (Use of Uninitialized Resource)
Vendor Openslide
Public PoC No

OpenSlide is a C library for reading whole slide image files. Prior to 4.0.1, a behavior change in libtiff 4.7.1 causes the indirect TIFF tile path in src/openslide-decode-tiff.c and _openslide_tiff_read_tile() to request a full-height destination for a partial bottom tile row, allowing uninitialized heap memory to enter pixel data returned by openslide_read_region(). A crafted but valid slide can trigger the issue in TIFF-based formats other than Hamamatsu NDPI when a network service renders attacker-provided slides.

Successful extraction depends on pixel transparency handling and recompression, OpenSlide with libtiff 4.7.0 or earlier is not affected, and official binary builds 4.0.0.10 and 4.0.0.11 are affected. This issue is fixed in OpenSlide 4.0.1 and official binary build 4.0.0.12.

Attack Parameters

Attack Vector
Network
Can be exploited remotely
Attack Complexity
Low
Easy to exploit
Attack Requirements
None
No additional conditions
Privileges Required
Low
Basic privileges needed
User Interaction
None
No user interaction needed

Impact Assessment

Confidentiality
Low
Partial data leak
Integrity
None
No data modification
Availability
None
No disruption

CVSS Vector v4.0

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